Hospital environmental hygiene is a complex process because it is influenced by several variables, such as the type of surface, incorrect disinfectant contact times, excessive dilution of disinfectant solutions, and potential biocide/antibiotic cross-resistance. In addition, it has been shown that the use of contaminated cloths and/or solutions promotes the spread of microorganisms between different environments [

In that regard, the World Health Organization has reiterated the importance of using this type of disinfection after the adoption of the standard protocol for sanitizing hospital rooms, but, during the COVID- pandemic, the use of UVC radiation was also proposed immediately after the patient has been discharged in order to reduce the risk of the cleaning staff being infected, who can then safely apply the standard protocol [

In our study, we evaluated the efficacy of the UV-C treatment only on the reduction in mesophilic growth that mainly represents human contamination, but not on specific pathogens of interest; however, the reduction was very significant, suggesting that this system can easily eliminate pathogens as well. We have previously demonstrated that the adoption of an automated UV-C-disinfection robot in the enhancement of SOP in high-risk settings was successful in reducing pathogens on high-touch surfaces, improving the patient&#x;s safety [

These organisms belong to a group of carbapenem-resistant, gram-negative bacteria of national and international concern because of their implication as an emerging cause of severe healthcare-associated infections. In , the World Health Organization published the first global guidelines for the prevention and control of CRE-CRAB-CRPsA in healthcare facilities, which include environmental cleaning and disinfection as a key recommendation.

Each hospital should have an infection control team aiming to evaluate the risk factors involved in healthcare infection occurrences with a multidisciplinary and dynamic approach. Epidemiological infection control in hospital may detect all of the critical points of the healthcare procedures performed by nurses, healthcare workers, physicians, students, and external staff. This evaluation may also include the sanitization process and its management. An appropriate evaluation of the whole sanitization process, including the reprocessing of cleaning materials, would be the best practice.